Hematopoietic lineage cell–specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation
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چکیده
منابع مشابه
Hematopoietic lineage cell specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation.
Collagen activates platelets through an intracellular signaling cascade downstream of glycoprotein VI (GPVI). We have investigated the contribution of hematopoietic lineage cell-specific protein 1 (HS1) downstream of GPVI in platelet activation. Stimulation of GPVI leads to tyrosine phosphorylation of HS1, which is blocked by Src-family kinase inhibitors. Coimmunoprecipitation experiments revea...
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ژورنال
عنوان ژورنال: Blood
سال: 2007
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2006-11-056069